Lanostane triterpenoids from Ganoderma hainanense J. D. Zhao.

نویسندگان

  • XingRong Peng
  • JieQing Liu
  • JianJun Xia
  • CuiFang Wang
  • XuYang Li
  • YuanYuan Deng
  • NiMan Bao
  • ZhiRun Zhang
  • MingHua Qiu
چکیده

Chemical investigation of the fruiting bodies of Ganoderma hainanense resulted in isolation of fourteen lanostane triterpenoids, including nine ganoderma acids and five ganoderma alcohols, together with five known compounds. Structural elucidation was determined using extensive spectroscopic technologies, Mosher's method and X-ray single crystal diffraction. Three of the compounds showed inhibitory activities against HL-60, SMMC-7721, A-549 and MCF-7 cells with IC50 values of 15.0-40.0 μM.

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عنوان ژورنال:
  • Phytochemistry

دوره 114  شماره 

صفحات  -

تاریخ انتشار 2015